Cannot setup new account on email server after update

After an update on the 10th jan we can no, not sure what one as there where many installed on that day.

1,  Via outlook change "Out of office Assistant"  we get the error "Your Out of Office setting cannot be displayed, becouse the server is currency unavailable"

2, setup new accounts in outlook as we get the same error " server is currency unavailable".

But we can send and receive emails.

We are using windows Server R2 2008 with Exchange server 2010.

Can someone please help